Comparison of Direct Healthcare Costs Associated with Chronic Spontaneous /Idiopathic Urticaria in 7 Countries - Results from the Assure-CSU Study

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The burden of chronic spontaneous urticaria is substantial: Real‐world evidence from ASSURE‐CSU

BACKGROUND Chronic spontaneous urticaria (CSU) can be debilitating, difficult to treat, and frustrating for patients and physicians. Real-world evidence for the burden of CSU is limited. The objective of this study was to document disease duration, treatment history, and disease activity, as well as impact on health-related quality of life (HRQoL) and work among patients with inadequately contr...

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ASSURE-CSU: a real-world study of burden of disease in patients with symptomatic chronic spontaneous urticaria

BACKGROUND Chronic spontaneous urticaria (CSU) formerly known as chronic idiopathic urticaria (CIU) is a severe and distressing skin condition that remains uncontrolled in approximately one half of patients, despite the use of licensed, recommended doses of modern, second-generation H1-antihistamines. So far, the humanistic, societal and economic burden of CSU/CIU has not been well quantified. ...

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Suppression of Basophil FcεRI Activation by Serum from Active Chronic Idiopathic/Spontaneous Urticaria (CIU/CSU) Subjects

Chronic idiopathic/spontaneous urticaria (CIU/CSU), which affects ~1% of the United States population, is defined as recurrent hives for >6 weeks (Kaplan and Greaves, 2009). Active CIU/CSU patients uniquely display suppressed basophil FcεRI-mediated histamine release (BHR) (Saini, 2014). This is a feature that improves in disease remission (Eckman et al., 2008; Kern and Lichtenstein, 1976; Oliv...

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Omalizumab in chronic spontaneous urticaria (CSU): experience in three cases

Background Chronic spontaneous urticaria (CSU) is more common in adults, especially middle-aged women. The condition resolves spontaneously within 6 months in 30 to 55% of patients but can persist for years in others. It has a devastating effect on the quality of life of those who experience it. Although the mechanisms are not fully elucidated, anti IgE recombinant humanized monoclonal (Omalizu...

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Resource Use and Costs in an Insured Population of Patients with Chronic Idiopathic/Spontaneous Urticaria

BACKGROUND Chronic idiopathic or spontaneous urticaria (CIU/CSU) impairs patients' quality of life, and updated information on disease prevalence, treatment patterns, and disease burden is lacking. OBJECTIVES We aimed to estimate these figures in a large US real-world claims database via a validated algorithm. METHODS In this retrospective cross-sectional cohort study, we identified patient...

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ژورنال

عنوان ژورنال: Value in Health

سال: 2016

ISSN: 1098-3015

DOI: 10.1016/j.jval.2016.09.1266